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San Francisco 49ers vs Arizona Cardinals result (16:15) on 22 Sep 2025 (NFL): 19 profitable pros on Polymarket/Kalshi took positions, 57% backing San Francisco 49ers to win. See who got it right, plus both teams' form.
Final score: San Francisco 49ers 16:15 Arizona Cardinals (2025-09-22). Before the result, 57% of 7 profitable pros with a win/draw position backed San Francisco 49ers to win — that call was right.
19 profitable pros (listed on Tips, cumulative P&L above zero) hold positions on this match. Latest win/draw pick per pro: San Francisco 49ers 4 (57%) · Arizona Cardinals 3 (43%).
Sources: public prices and positions on Polymarket and Kalshi; results from public sports data. Data as of 2025-09-22 07:14 UTC+8. How we calculate: methodology
19 profitable pros have positions on this match. Latest win/draw pick per pro: San Francisco 49ers to win 4 (57%) · Arizona Cardinals to win 3 (43%).
| Date | Match | Pick | Result |
|---|---|---|---|
| 2025-09-22 | RBP Polymarket | Cardinals to win | Lost |
| 2025-09-22 | IloveSt0rm Polymarket | 49ers to win | Won |
| 2025-09-22 | asd1234567 Polymarket | Cardinals to win | Lost |
| 2025-09-22 | abustle Polymarket | 49ers to win | Won |
| 2025-09-22 | anon.astronaut Polymarket | 49ers to win | Won |
| 2025-09-22 | ilovecircle Polymarket | 49ers to win | Won |
| 2025-09-22 | Glued Polymarket | 49ers to win | Won |
| 2025-09-22 | Geo9 Polymarket | ARI vs SF O/U 51.5 | Won |
| 2025-09-21 | 0x5b34…eb42 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x8268…a0a1 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x8268…a0a1 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x3aa9…e9e2 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xb185…a5da SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xfe17…11b0 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0xfe17…11b0 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x5b34…eb42 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0xb054…f202 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x3151…8373 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0xfd3a…0b17 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x4791…4f0e SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x6d15…aa4a SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0xb054…f202 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x7017…00c7 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x7017…00c7 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x541c…9edb SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x5b34…eb42 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x4332…df5d SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x5b34…eb42 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x6d15…aa4a SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0x10d8…db68 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |
| 2025-09-21 | 0xb185…a5da SX Bet | San Francisco 49ers vs Arizona Cardinals | Won |
| 2025-09-21 | 0x68e1…bd35 SX Bet | San Francisco 49ers vs Arizona Cardinals | Lost |